Aluminum phosphide was first registered as a pesticide in the U.S. in 1958 to Hollywood Termite Control Company, Inc. AlP is used as a rodenticide, insecticide and fumigant for stored cereal grains. Pure phosphine is odorless, but technical grade phosphine has a highly unpleasant odor like garlic or rotting fish, due to the presence of substituted phosphine and diphosphine (P2H4). While baits incorporating zinc phosphide are the primary formulation for killing rodents, the occupational exposure of fumigators to phosphine gas has caused a number of fatal incidents. Deaths have occurred in animals as a result of repeated daily exposures to concentrations below acutely injurious concentrations [42,43]. d. Structure, properties, spectra, suppliers and links for: Aluminium phosphide, 20859-73-8. Magnesium and aluminium phosphide release phosphine (PH3) on contact with water. © 1997-2020 LUMITOS AG, All rights reserved, https://www.chemeurope.com/en/encyclopedia/Aluminium_phosphide.html, Your browser is not current. The acid in the digestive system of the rodent reacts with the phosphide to generate the toxic phosphine gas. Aluminum phosphide is used as a fumigant to protect stored grain from insects and rodents. This colourless solid is generally sold as a grey-green-yellow powder due to the presence of impurities arising hydrolysis and oxidation. In man this cumulative effect is not proven [44]. Crude aluminium phosphide can be prepared in the laboratory by igniting a mixture of red phosphorus and powdered aluminium. AlP inhibits cytochrome oxidase, interferes with cellular respiration, and induces severe oxidative stress. The National Institute for Occupational Safety and Health immediately dangerous to life or health value for phosphine is 50 ppm. Other pesticides similar to aluminium phosphide are zinc phosphide and calcium phosphide. Aluminum phosphide. In addition liver and renal damage, thrombopenia, and death can ensue within 3–14 days. Magnesium and aluminium phosphide are used for fumigation in pest control, and zinc phosphide as a rodenticide. There is no effective antidote available, and the incidence of death secondary to exposure has been increasing Phosphine inhibits mitochondrial cytochrome oxidase. Samples must be submitted frozen in air-tight containers for analysis of phosphine. Two children and 29 of 31 crew members aboard a grain freighter became acutely ill after inhaling phosphine originating from aluminum phosphide. 2 matches found for Aluminium Phosphide . (2012) performed a two-stage study in which aluminum chloride–phthalocyanine (AlClPc) was delivered in cationic liposomes as the PS. Find out more about the company LUMITOS and our team. Microscopic findings in rare cases with histologic sampling include extensive necrosis, mixed acute and chronic inflammation, arteriolar endothelial swelling, and edema. Phosphine is absorbed following inhalation. Although the registrant’s name was changed subsequently, the original U.S. aluminum phosphide registration remains active. They concluded that PDT using AlClPc-cationic liposomes is an effective and also clinically safe approach to attenuate the bacterial count in caries. In the presence of moisture, aluminum phosphide releases phosphine, which is highly toxic. Wood, in Encyclopedia of Toxicology (Third Edition), 2014. The Occupational Safety and Health Administration permissible exposure limit for phosphine is 0.3 ppm (averaged over an 8-h work shift). Aluminum phosphide (AlP) is a highly effective outdoor and indoor insecticide and rodenticide. RTECS # BD1400000 CAS # 20859-73-8; 1302-45-0; 71751-04-7 See: NMAM or OSHA Methods. All domestic animals can be affected and reports are common in dogs. After moving the patient into fresh air, recovery will usually be rapid. Phosphine is a colourless gas at room temperature and normal atmospheric pressure. No data available on solubility in other solvents, Phosphine: Formula, PH3; MW, 34.00; BP, −87.7°C; log P, NA; VP, 2.93 × 10+4 mm Hg; other solubilities: soluble in alcohol, ether, and cuprous chloride solution. Magnesium phosphide (Mg3P2), aluminium phosphide (AIP) and zinc phosphide (ZnsP2), are phosphorus preparations which have found a specific place in rodent control. The reference concentration for phosphine is 0.0003 mg m−3. Aluminium phosphide is the chemical compound with the formula AlP. In the poisoned patient abdominal pain, vomiting and restlessness are common initial features, followed by alteration in sensorium, hypotension, and cardiac arrhythmias. However, it is still used in certain countries to help protect stored grains from pets and rodents. Exposure to 1400 mg/m3 (1000 ppm) for 30 minutes may be fatal. CDC twenty four seven. Pure phosphine is inflammable at 100°C.