George, D. R., Sparagano, O. J Am Geriatr Soc 2006;54(9):1401-1406.View abstract. Some medications changed by the liver include cyclophosphamide, ifosfamide, barbiturates, bromobenzene, and others. View abstract. Drugs R.D. Cancer Lett. Selvendiran, K., Singh, J. P., Krishnan, K. B., and Sakthisekaran, D. Cytoprotective effect of piperine against benzo[a]pyrene induced lung cancer with reference to lipid peroxidation and antioxidant system in Swiss albino mice. Reduction of neurite extension by piperine, examined on hippocampal and septal neurons in serum-free cultures. Mil.Med. 2000;48(4):1340-1344. View abstract. Hu, Y., Liao, H. B., Liu, P., Guo, D. H., and Wang, Y. Y. View abstract. Indian J Exp.Biol. J Agric.Food Chem. View abstract. Antioxidant consumption may also reduce the risk of certain cancers as well as heart disease. View abstract. 2-13-2007;80(10):926-931. 1992;112(2):138-143. Shenoy, N. R. and Choughuley, A. S. Characterization of potentially mutagenic products from the nitrosation of piperine. D'Cruz, S. C. and Mathur, P. P. Effect of piperine on the epididymis of adult male rats. Ghadirian, P., Ekoe, J. M., and Thouez, J. P. Food habits and esophageal cancer: an overview. Hamada, T. [Studies on the crude drugs used for the folk medicine described in "mimi-bukuro"]. Mujumdar, A. M., Dhuley, J. N., Deshmukh, V. K., Raman, P. H., Thorat, S. L., and Naik, S. R. Effect of piperine on pentobarbitone induced hypnosis in rats. Ai.Zheng. While large amounts of red pepper could cause gut irritation in susceptible people, it does not have the potential damaging effect that black pepper has and offers many positive therapeutic properties. Neurourol.Urodyn. Lee, S. W., Kim, Y. K., Kim, K., Lee, H. S., Choi, J. H., Lee, W. S., Jun, C. D., Park, J. H., Lee, J. M., and Rho, M. C. Alkamides from the fruits of Piper longum and Piper nigrum displaying potent cell adhesion inhibition. If I were there when they named chili peppers, I would have stopped that from happening. Siebert, T. E., Wood, C., Elsey, G. M., and Pollnitz, A. P. Determination of rotundone, the pepper aroma impact compound, in grapes and wine. Jeannel, D., Hubert, A., de Vathaire, F., Ellouz, R., Camoun, M., Ben Salem, M., Sancho-Garnier, H., and de The, G. Diet, living conditions and nasopharyngeal carcinoma in Tunisia--a case-control study. Proc Natl.Sci Counc.Repub.China B 1986;10(1):20-34. 2007;40(4):405-407. 7-5-2004;14(13):3555-3558. Rentmeister-Bryant, H. and Green, B. G. Perceived irritation during ingestion of capsaicin or piperine: comparison of trigeminal and non-trigeminal areas. Piyachaturawat, P., Sriwattana, W., Damrongphol, P., and Pholpramool, C. Effects of piperine on hamster sperm capacitation and fertilization in vitro. The effect of piperine on pharmacokinetics of phenytoin in healthy volunteers. Turmeric is an old Indian spice with a powerful medicinal compound called Curcumin. View abstract. Many delicious ingredients are also exceptionally healthy. View abstract. View abstract. J Med.Food 2006;9(2):237-245. View abstract. Pathak, N. Immunomodulatory role of piperine in cadmium induced thymic atrophy and splenomegaly in mice. A., Romeiro, A., Mendonca-Previato, L., Previato, J. O., de Lima, M. E., de Carvalho, T. M., and Heise, N. The toxic effects of piperine against Trypanosoma cruzi: ultrastructural alterations and reversible blockage of cytokinesis in epimastigote forms. Phytomedicine. White pepper is made by cooking and drying the ripe seeds. People take black pepper by mouth for arthritis , asthma , upset stomach , bronchitis , a bacterial infection that causes diarrhea ( cholera ), colic , depression , diarrhea, gas, headache , sex drive, menstrual pain , stuffy nose , sinus infection, dizziness , discolored skin ( vitiligo ), weight loss , and … Until more is known, monitor your blood sugar closely if you take black pepper. Omissions? View abstract. Dorman HJ, Deans SG. At this time there is not enough scientific information to determine an appropriate range of doses for black pepper (in children/in adults).